Apples : Urosolic Acid

Apple skin nutrient curbs disease associated with metabolic syndrome.

apple nutrients for diabetes diet supplement and metabolic syndromeI have previously posted on the positive health benefits of apples in the diabetes diet and prediabetes metabolic syndrome management.  Here is more scientific justification for the adage, “an apple a day helps keep the doctor away.”  A study in the June 2011 Cell Metabolism has identified a nutrient compound in apples that appears to help prevent the muscle wasting that can result from aging and illness. The beneficial nutrient compound is actually found in the apple skin and is called ursolic acid.

This nutrient was identified by looking at mouse genes that are regulated by fasting and spinal cord injury. The researchers then identified urosolic acid through a data base known as the Connectivity Map that singled out urosolic acid as a compound that might counteract muscle atrophy.

The researchers then found that ursolic acid could protect against muscle wasting in the mice that were deprived of food. They also found that adding ursolic acid to the food of normal mice for a number of weeks not only stopped wasting, but stimulated muscle growth.

In addition, mice that received ursolic acid had reductions in fat, fasting blood glucose, cholesterol and triglycerides.

As always, it is not yet known how these findings would translate to humans. Nevertheless, add apples to your diet, especially the diabetic diet and also for the management of prediabetes metabolic syndrome.

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About Robert Creighton

Dr. Creighton is a podiatrist and foot surgeon with over 26 years in podiatric practice treating thousands of patients afflicted with the physiological, physical, and psychological side effects and complications of diabetes and pre-diabetes metabolic syndrome. He believes these disorders present a pressing public health concern that need to be more actively addressed in a multidisciplinary way. Dr. Creighton graduated from what is now the Temple University School of Podiatric Medicine after receiving his undergraduate degree in Biology. He is certified by the American Board of Foot and Ankle Surgery, a member of the American Public Health Association, an American College of Sports Medicine certified personal trainer and a Member of the American Nutrition Association.

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