Liquorice root shown to contain compounds with anti-diabetic effect

Liquorice root and another legume shown to provide an anti-diabetic effect with beneficial effect on blood sugar. Food is medicine to stop prediabetes.

liquorice root shown to help prediabetes blood sugarA study using an animal model demonstrated a positive metabolic response from compounds called amorfrutins. These compounds were identified and tested in two common legumes:

1. Glycyrriza foetida – found in the plant root from which liquorice is derived.
2. Amorpha fruticosa – commonly called False Indigo-bush. It can be found in parts of U.S., Canada and Mexico. Amorfrutins were found in the fruit.

Amorfrutins were shown to favorably interact with a receptor that plays an important role in the metabolism of fats and sugars “deep down inside” the cells of your body where your DNA resides – this area is known as the nucleus. These two legume amorfrutins showed a positive influence on insulin resistance and inflammation. Some prescription medicines used to control blood sugar levels in Type 2 diabetics act on the same receptor as the amorfrutins. Derivatives of amorfrutins may one day be used as more potent prescription medicines.

While these two legumes certainly are not a replacement for needed medications to help manage your blood sugar, these findings support the “food as medicine” concept. Many people view food simply as a source of energy. They do not think about the physiologic interaction, either positive or negative, that can take place inside the cells of the body – even down to your DNA – from the food you eat. Food can, and will, impact your metabolism for better or worse.

If you have prediabetes metabolic syndrome, changing your mindset and thinking about food as medicine with a healing potential is a good first step on your road to recovery.


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About Robert Creighton

Dr. Creighton is a podiatrist and foot surgeon with over 26 years in podiatric practice treating thousands of patients afflicted with the physiological, physical, and psychological side effects and complications of diabetes and pre-diabetes metabolic syndrome. He believes these disorders present a pressing public health concern that need to be more actively addressed in a multidisciplinary way. Dr. Creighton graduated from what is now the Temple University School of Podiatric Medicine after receiving his undergraduate degree in Biology. He is certified by the American Board of Foot and Ankle Surgery, a member of the American Public Health Association, an American College of Sports Medicine certified personal trainer and a Member of the American Nutrition Association.

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